CD95 Antigen
The CD95 (Fas or APO-1) antigen is a 40-50 kDa transmembrane glycoprotein. It belongs to the Tumor Necrosis Factor (TNF) superfamily and contains three cysteine-rich repeats. This cell surface molecule mediates apoptosis (programmed cell death). CD95 antigen is expressed on a substantial proportion of peripheral blood CD4+ lymphocytes, CD8+ lymphocytes and B lymphocytes but on a minor proportion of NK cells. It is not found on platelets or erythrocytes, but is expressed variably on granulocytes and monocytes. CD95 is strongly up-regulated on activated T cells, B cells, NK cells and thymocytes. Moreover, it is widely expressed on cell lines of T, B, NK and myeloid lineages. Most other tissues express CD95.
Clone: CH11 | Isotype: IgM Mouse |
The CH11 antibody in vitro induces apoptosis in some CD95 expressing cell lines. |
Clone: UB2 | Isotype: IgG1 Mouse |
Choose a CD95 Model
Product Line Specifications
Format | Liquid |
Specificity | CD95 |
Form | PE |
Clone | UB2 |
Isotype | IgG1 Mouse |
Cross Reactivity | Carp |
Target Species | Human |
Item Specifications Referenced | IM1739 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.