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The CD14 antigen is a glycosyl-phosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high affinity receptor for the complex of LipoPolySaccharide (LPS) and the LPS-Binding Protein (LBP). It is found on cells of myelomonocytic lineage. CD14 antigen is strongly expressed on monocytes, macrophages, and weakly on neutrophils. It is also weakly expressed on B lymphocytes, but is absent from T lymphocytes, NK cells, red blood cells and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes.
Specifications
Target Species
Human
Specificity
CD14
Other Names
CD14, LPS Receptor
Fluorochrome
APC
Regulatory Status
ASR
Size
1 mL
Format
Liquid
Flow Product Line
IOTest
Clone
RMO52
Isotype
IgG2a Mouse
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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS
The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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