CD5 Antigen

CD5 is a type I transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of nearly 100 amino acids each. The CD5 is expressed at the surface of mature T lymphocytes, by most of thymocytes and by a subpopulation of B lymphocytes (B-1a) expanded in neonatal life, several autoimmune disorders and some B-cell proliferative disorders (B-CLL). It is not found on granulocytes, monocytes and platelets. The CD5 antigen is the ligand for the B-lymphocytes cell-surface protein CD72. The CD5 / CD72 interactions are involved in the regulation of T and B lymphocyte activation and proliferation. B lymphocytes can be divided into B-1 lymphocytes and B-2 (or conventional B) lymphocytes based on different localization, functional characteristics and gene expression. The B-1 lymphocyte subset is divided into B-1a and B-1b subpopulations, which do or do not express the CD5 antigen respectively. The B-1a CD5+ B lymphocyte subset expresses immunoglobulin with inherent low affinities for self-antigens.


Clone: BL1a  Isotype: IgG2a Mouse

BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA/6.

Clone: CLB-T1/1 Isotype: IgG2a Mouse





Choose a CD5 Model



Product Line Specifications

Format Liquid
Specificity CD5
Form Pacific Blue*
Clone BL1a
Isotype IgG2a Mouse
Cross Reactivity Bovine, Equine
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced A82790

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Technical Documents