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The CD5 antigen is a single-chain transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of approximately 100 amino acids each. CD5 is found on all mature T lymphocytes and on most thymocytes. CD5 is also present on a B lymphocyte subset but is not found on granulocytes or monocytes. CD5 is a ligand for the CD72 antigen, which is present on B lymphocytes. The CD5+ B lymphocyte subset (known as B-1a lymphocytes) may arise from a non-conventional B lineage (independent of bone marrow).
CD5, CD72 Ligand, T1, Tp67
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BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA/6.
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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.
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